Which of the Following Describes How the Hygiene Hypothesis Is

Which of the following describes how the hygiene hypothesis is related to type I hypersensitivity reactions?

A) Between 1997 and 2011, the incidence of food allergies in the United States increased by 50 percent.
B) Children living on a farm are 25 percent more likely to experience seasonal allergies than children living in a large city.
C) Food allergies have increased 3- fold in chronically poor families as compared to wealthy families in the United States.
D) Up to 30 percent of people in undeveloped countries suffer from allergic rhinitis.
E) Wealthy individuals are 10 times more likely to experience anaphylactic shock as compared to someone raised in an orphanage during adolescences.