For the Byzantine Empire, which of the following was a negative impact of trade connections to the east?

Name: For the Byzantine Empire, which of the following was a negative impact of trade connections to the east?
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The outbreak of bubonic plague during Justinian's reign was a direct negative impact of trade connections to the east, as the disease was brought to the Byzantine Empire through trade ships coming from the east, particularly affecting the empire's population and economy severely.

For the Byzantine Empire, Which of the Following Was a Negative