In 1900, most deaths in the United States were caused by infectious diseases. By 2000, the leading causes of death were more often chronic non-infectious) diseases.

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In 1900, infectious diseases were the leading cause of death due to poor sanitation and lack of antibiotics. By 2000, improvements in public health, vaccination, and antibiotics had significantly reduced deaths from infectious diseases, making chronic non-infectious diseases like heart disease and cancer the leading causes of death.

In 1900, Most Deaths in the United States Were Caused