Loop diuretics reduce body water content by acting on
A)the feedback loop between the kidney and posterior pituitary gland.
B)the countercurrent multiplier system.
C)the countercurrent exchanger system.
D)aquaporins of the collecting duct.
E)the thirst mechanism and water intake.

Question

Quizplus · Accepted Answer

Loop diuretics act on the countercurrent multiplier system by inhibiting the Na-K-2Cl symporter in the thick ascending limb of the loop of Henle, reducing reabsorption of sodium, chloride, and potassium, leading to increased urine production and reduced body water content.

Loop Diuretics Reduce Body Water Content by Acting on