Peptide hormones generally are synthesized
A) In the liver
B) As larger precursor proteins that are proteolytically cleaved to become active
C) In the Golgi apparatus
D) On the smooth ER
E) In secretory vesicles

Question

Quizplus · Accepted Answer

Peptide hormones are typically synthesized as larger precursor proteins, known as preprohormones, which undergo proteolytic cleavage to remove signal sequences and convert them into their active forms. This process often occurs in the endoplasmic reticulum and Golgi apparatus before the hormones are packaged into secretory vesicles.

Peptide Hormones Generally Are Synthesized