Contraction of vascular smooth m uscle is controlled by A) Myosin light chain kinase B) Myosin light chain phosphatase C) The state of light chain phosphorylation D) Ca²⁺ binding to calmodulin that activates MLCK E) All of the above

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Quizplus · Accepted Answer

All of the options listed are involved in the control of vascular smooth muscle contraction. Myosin light chain kinase (MLCK) phosphorylates myosin light chains, which is a key step in muscle contraction. Myosin light chain phosphatase dephosphorylates these chains, leading to relaxation. The state of light chain phosphorylation (whether they are phosphorylated or not) directly determines the contraction state of the muscle. Ca2+ binding to calmodulin activates MLCK, which is a crucial step in the contraction process. Therefore, all these components play a role in the regulation of vascular smooth muscle contraction.

Contraction of Vascular Smooth M Uscle Is Controlled by