Pharmacom echanical coupling develops smooth muscle force by A) Release of Ca₂+ via G B) Voltage-gated Ca₂+ ch an ne ls a ctiv ate d b y ac tion po ten tials C) Voltage-gated Ca₂+ channels activated by mem brane potential change without action po ten tials D) Ca₂+ release through RyR E) Ca₂+ uptake into the SR m ediated by phospholamban phosphorylation

Question

Quizplus · Accepted Answer

Pharmacomechanical coupling in smooth muscle involves the release of Ca₂+ via G-protein coupled receptors, which activate intracellular signaling pathways leading to Ca₂+ release from the sarcoplasmic reticulum without the need for membrane depolarization or action potentials.

Pharmacom Echanical Coupling Develops Smooth Muscle Force by