The clearance of inulin is 100 mL min^-1 in a patient. His plasm a concentration of solute X is 0.2mg% and a 4-hour urine specimen was 240 m L, with a urinary concentration of solute X of 60 mg% . From this information you can conclude A) Substance X is not freely filtered B) Substance X is reabsorbed C) Substance X is secreted D) Substance X is both filtered and secreted E) Substance X is both freely filtered and reabsorbed

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Quizplus · Accepted Answer

DThe clearance of a substance can indicate whether it is filtered, reabsorbed, or secreted by the kidneys. Inulin clearance is used as a measure of glomerular filtration rate (GFR) because it is freely filtered and neither reabsorbed nor secreted. If the clearance of substance X is higher than that of inulin, it suggests that X is not only filtered but also secreted. The given data shows that substance X has a much higher concentration in the urine compared to its plasma concentration, indicating active secretion into the urine. Additionally, since it appears in the urine, it must also be filtered, hence both filtered and secreted.

The Clearance of Inulin Is 100 ML Min-1 in a Patient

The Clearance of Inulin Is 100 ML Min^-1 in a Patient