Phenytoin and folic acid use the same binding sites in the body. If an increased intake of folic acid inhibits phenytoin therapy to the extent that seizure activity increases, the effect is termed

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Phenytoin and folic acid compete for the same binding sites in the body. If an increased intake of folic acid inhibits phenytoin therapy to the extent that seizure activity increases, the effect is termed a pharmacodynamic interaction.

Phenytoin and Folic Acid Use the Same Binding Sites in the Body