Which complement protein is the key to the activation of the alternative pathway of complement activation?

Name: Which complement protein is the key to the activation of the alternative pathway of complement activation?
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Question

Quizplus · Accepted Answer

C3 is the key protein in the activation of the alternative pathway of complement activation. It undergoes spontaneous hydrolysis to form C3(H2O), which can then bind factor B, leading to the formation of the C3 convertase that amplifies the pathway.

Which Complement Protein Is the Key to the Activation of the Alternative