All of the Following Statements Concerning Development of Antibiotic Resistance

All of the following statements concerning development of antibiotic resistance are true EXCEPT:

A) resistant cells are normally in the minority in a bacterial population.
B) it is often mediated by R- plasmids.
C) new resistance genes can be gained through transformation, transduction, or conjugation.
D) resistance can occur through mutation of existing bacterial genes.
E) resistant cells grow more efficiently and quickly than susceptible cells.