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Tim and Mary Are Planning to Start a Familiy

Question 52

Essay

Tim and Mary are planning to start a familiy. While neither of them have cystic fibrosis, a rare autosomal recessi disease, they are concerned that their children could have the disease since Tim's father, John, AND Mary's broth Ralph both have the disease.
a. Draw a pedigree of the inheritance of the cystic fibrosis allele in this family.
b. On your pedigree, indicate any individuals that must be carriers.
c. What is the probability that Tim will be a carrier for the disease allele?
d. What is the probability that Mary will be a carrier for the disease allele?
e. What is the probability that Tim and Mary will have a child with the disease?

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