Which of the following can be mutated to result in constitutive expression from the lac operon?
A) lacO and lacI
B) lacO and lacZ
C) lacI and lacY
D) lacZ and lacI
E) lacZ and lacP

Question

Quizplus · Accepted Answer

Mutations in both lacO (the operator site) and lacI (the gene coding for the repressor protein) can lead to constitutive expression from the lac operon. A mutation in lacO can prevent the repressor from binding, and a mutation in lacI can result in a non-functional repressor, both leading to continuous expression of the operon.

Which of the Following Can Be Mutated to Result in Constitutive