A chromosome contains the following gene order:
A B C D • E F G H
Which of the following rearrangements represents a pericentric inversion?
A) A B C D • E F G H
B) A F G H B C D • E
C) A F E • D C B G H
D) A C B D • E F G H
E) A B C D • E H G F

Question

A chromosome contains the following gene order: 
A B C D • E F G H 
Which of the following rearrangements represents a pericentric inversion?
A) A B C D • E F G H
B) A F G H B C D • E
C) A F E • D C B G H
D) A C B D • E F G H
E) A B C D • E H G F

Quizplus · Accepted Answer

EPericentric inversions involve a segment of the chromosome that includes the centromere and results in the inversion of the segment's gene order. Choice C shows a pericentric inversion because the segment including and surrounding the centromere (indicated by •) has been inverted, changing the order of the genes on both sides of the centromere. Choice E also represents a pericentric inversion because it inverts the gene order around the centromere, flipping the segment E H G F while maintaining the centromere's position.

A Chromosome Contains the Following Gene Order