One Reason Why Neonatal Exposure to Alcohol or the Drugs

One reason why neonatal exposure to alcohol or the drugs of abuse in the first trimester is potentially dangerous is because _.

A) this is a time of organ differentiation and rapid growth of these immature organs, making them especially vulnerable to toxins in the fetal circulation
B) although the neonate's liver is fully developed, it is too small to cope with the doses of alcohol or illicit drugs used by an adult
C) the fetus' liver can biotransform these compounds faster than maternal circulation can accept them for transport to the kidneys, forcing them to back up in the fetal circulation
D) these compounds all increase maternal blood flow rates so much that the fetal circulation is overwhelmed and fetal blood pressure rises