The Client Has an Extensive History of Alcoholism

The client has an extensive history of alcoholism.He is having coronary bypass surgery.While administering anesthesia, the certified nurse anesthetist notes that the client requires greater-than-usual amounts of the drug.The nurse correctly evaluates this response as what phenomenon?

A) The client has developed a paradoxical reaction to the anesthesia, and will require a different drug.
B) The nurse anesthetist most likely did not calculate the correct amount of anesthesia for this client.
C) The client has developed a resistance to the anesthesia, so it will not work very well.
D) The client had developed cross-tolerance to the anesthesia, and will require greater amounts.