The nurse explains to a student nurse that the mean lethal dose of drugs is often determined in laboratory preclinical trials for the following reasons: (Select all that apply.)
A) It would be unethical to determine these values in human subjects.
B) It is too costly to conduct the studies during clinical trials.
C) Safety of the medication must be determined prior to clinical trials.
D) It is difficult to obtain sufficient participants for clinical trials.
E) Clinical trials only determine the effective dose of a drug.
Correct Answer:
Verified
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