A Nurse Understands That a Patient Placed on Reverse Isolation

A nurse understands that a patient placed on reverse isolation might exhibit signs of depression because:

A) The patient always becomes claustrophobic.
B) The patient might believe that she has to be in isolation because her cancer is contagious, so family won't want to visit her.
C) Patients in reverse isolation often have additional side effects to therapy.
D) Patients in reverse isolation often have a more severe form of cancer.