All of the Following Are Mechanisms by Which Resistance to Fluoroquinolones

All of the following are mechanisms by which resistance to fluoroquinolones occurs except that:

A) Bacterial cell walls become less permeable to the fluoroquinolones.
B) Certain bacteria have developed resistance pumps that remove fluoroquinolones from the cell.
C) Mutations to DNA gyrase alter its ability to bind with fluoroquinolones.
D) Mutations to DNA helicase alter its ability to bind with fluoroquinolones.