A client has been started on diltiazem (Cardizem) , a susbstrate of the cytochrome CYP3A4 isoenzyme system.Since the client also takes Phenobarbital for seizures, which is an inducer of the CYP3A4 isoenzyme system, the nurse recognizes that diltiazem:
A) Will not be able to cross the blood brain barrier (BBB) .
B) Might be inactivated at a faster rate than normal.
C) Might be excreted at a slower rate.
D) Will be metabolized by the kidneys.
Correct Answer:
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