The appropriate folding of a newly translated protein is essential, and chronic misfolding often leads to disease, especially in vertebrates. This misfolding, particularly in the case of prion diseases, may be due to a defect in
A)proteosome function.
B)translocase.
C)the enzyme foldase.
D)insertion of proper amino acids during translation.
E)chaperone activity.

Question

Quizplus · Accepted Answer

Chaperones are proteins that assist in the proper folding of other proteins. Defects in chaperone activity can lead to protein misfolding, which is a characteristic of prion diseases.

The Appropriate Folding of a Newly Translated Protein Is Essential