The first-line antibiotic choice for a patient with comorbidities or who is immunosuppressed who has pneumonia and can be treated as an outpatient would be:

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Levofloxacin is a fluoroquinolone antibiotic that has broad-spectrum activity, including coverage for common pathogens responsible for community-acquired pneumonia. It is often chosen for outpatient treatment of pneumonia in patients with comorbidities or who are immunosuppressed because of its effectiveness against a wide range of bacteria and its good penetration into lung tissues.

The First-Line Antibiotic Choice for a Patient with Comorbidities or Who