A Patient Who Is Receiving Medication-Assisted Treatment for Opioid Use

A patient who is receiving medication-assisted treatment for opioid use disorder with clonidine should begin treatment by:

A) Applying a clonidine patch three days before quit date
B) Using oral clonidine for three days until the clonidine patch reaches effective dosing
C) Taking clonidine 0.2 mg three times a day if the Clinical Opiate Withdrawal Scale (COWS) score is over 12
D) Maintaining clonidine dose at a steady state for a week then tapering over two weeks