A patient is taking lamotrigine (Lamictal) for their seizures and requests a prescription for combined oral contraceptives (COCs), which interact with lamotrigine and may cause:

Question

Quizplus · Accepted Answer

DCombined oral contraceptives (COCs) can reduce the levels of lamotrigine in the body due to hepatic enzyme induction, potentially decreasing the effectiveness of lamotrigine in controlling seizures. This may necessitate an increase in the lamotrigine dose to maintain therapeutic levels. Additionally, COCs can induce the metabolism of estrogen, which might require prescribing OCs with higher estrogen content to maintain contraceptive efficacy.

A Patient Is Taking Lamotrigine (Lamictal) for Their Seizures and Requests