When prescribing an opioid analgesic such as acetaminophen and codeine (Tylenol #3), instructions to the patient should include:

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All of the options listed are important instructions for a patient being prescribed an opioid analgesic like acetaminophen and codeine (Tylenol #3). Opioids can cause sedation, making activities such as driving unsafe. Constipation is a well-known side effect of opioids, and increasing fluid and fiber intake can help mitigate this issue. Additionally, because Tylenol #3 contains acetaminophen, patients should avoid taking other acetaminophen-containing medications concurrently to prevent overdose and potential liver damage.

When Prescribing an Opioid Analgesic Such as Acetaminophen and Codeine