A mutation in a promoter region that causes the promoter sequence to more closely resemble the
consensus sequence is called a up promoter mutation and decreases transcription.

Question

Quizplus · Accepted Answer

An up promoter mutation increases transcription because it makes the promoter more similar to the consensus sequence, enhancing the binding of RNA polymerase and other transcription factors.

A Mutation in a Promoter Region That Causes the Promoter