What are some diseases associated with imprinting?
A)Angelman Syndrome
B)LHON
C)Alzheimer's Disease
D)All of the answers are correct

Question

Quizplus · Accepted Answer

Angelman Syndrome is a disease associated with imprinting, caused by the loss of function of the maternally-inherited UBE3A gene. This gene is imprinted, meaning it is only active when inherited from the mother's chromosome 15. If the maternal copy of UBE3A is deleted or mutated, individuals develop Angelman Syndrome, which is characterized by intellectual disability, severe speech impairment, and motor abnormalities.

Answer: D
 LHON (Leber's Hereditary Optic Neuropathy) is a mitochondrial disorder and Alzheimer's Disease is a neurodegenerative disorder, neither of which are associated with imprinting. Therefore, the best choice is D, as Angelman Syndrome is a disease associated with imprinting.

What Are Some Diseases Associated with Imprinting