The glycolytic pathway oxidizes glucose to two molecules of pyruvate and also produces a net of two molecules of ATP.ATP allosterically inhibits the enzyme,PFK-1,that catalyzes the third step of glycolysis.This is an example of ________.
A)feed-forward activation
B)feedback inhibition
C)negative cooperativity
D)competitive inhibition

Question

Quizplus · Accepted Answer

The fact that ATP allosterically inhibits the enzyme, PFK-1, which is involved in the glycolytic pathway, is an example of feedback inhibition. This is because an end product of the pathway (ATP) inhibits one of the enzymes that is involved in the pathway itself, thereby regulating the rate of the pathway.

The Glycolytic Pathway Oxidizes Glucose to Two Molecules of Pyruvate