For normal mitochondria in the presence of an oxidizable substrate and an uncoupler such as 2,4-dinitrophenol which do you expect?
A) oxygen consumption even in the absence of ADP
B) a rise in temperature to dissipate energy that would otherwise have been used to generate ATP
C) the flow of protons into the mitochondria matrix
D) All of the above
E) None of the above

Question

Quizplus · Accepted Answer

Uncouplers like 2,4-dinitrophenol disrupt the proton gradient, leading to continuous oxygen consumption and heat production as energy is dissipated instead of being used for ATP synthesis.

For Normal Mitochondria in the Presence of an Oxidizable Substrate