The Main Treatment for Depression Is Drugs, of Which the Principal

The main treatment for depression is drugs, of which the principal kinds are selective serotonin reuptake inhibitors (SSRIs) . The drugs function by ____________________________. Irving Kirsch's (2009) meta-analysis of SSRI drug trials suggests that, compared with placebos, SSRIs have ________________ effect on depression.

A) boosting the amount of serotonin that is released by neurons; a moderate to large
B) boosting the amount of serotonin that is released by neurons; either no effect or a tiny
C) reducing the reabsorption of serotonin so that it remains in synapses for longer; a moderate to large
D) reducing the reabsorption of serotonin so that it remains in synapses for longer; either no effect or a tiny