Are most chromosomal abnormalities lethal or nonlethal?

Question

Quizplus · Accepted Answer

Most chromosomal abnormalities are lethal and result in spontaneous abortion, either during the first trimester or later in pregnancy. This is due to the fact that chromosomal abnormalities often result in developmental defects that are not compatible with life. While some chromosomal abnormalities, such as Down syndrome or fragile-X syndrome, are nonlethal, they are the exception rather than the rule.

Are Most Chromosomal Abnormalities Lethal or Nonlethal