After major reconstructive surgery,a patient's wounds dehisced.Extensive wound care was required for 6 months,causing the patient to miss work and social activities.Which pathophysiology would be expected for this patient? Dysfunction of the:

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The scenario presents chronic and potentially debilitating stress.If arousal continues unabated,neuronal changes occur that alter the neural circuitry of the prefrontal cortex,reducing the size the hippocampus so that memory is impaired.

After Major Reconstructive Surgery,a Patient's Wounds Dehisced