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An Adverse Drug Effect (ADE)is an Unintended Injury Caused by Prescribed

Question 8

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An adverse drug effect (ADE) is an unintended injury caused by prescribed medication. The table summarizes the proximal cause of 95 ADEs that resulted from a dosing error at a Boston hospital.  WRONG DOSAGE USE  NUMBER OF ADEs  (1)  Lack of knowledge of drug 29 (2)  Rule violation 17 (3)  Faulty dose checking 13 (4)  Slips 9 (5)  Other 27 TOTAL 95\begin{array}{lc}\hline \text { WRONG DOSAGE USE } & \text { NUMBER OF ADEs } \\\hline \text { (1) Lack of knowledge of drug } & 29 \\\text { (2) Rule violation } & 17 \\\text { (3) Faulty dose checking } & 13 \\\text { (4) Slips } & 9 \\\text { (5) Other } & 27 \\\hline \text { TOTAL } & 95\end{array}

In order to determine whether the true percentages of ADEs in the five "cause" categories differ, a chi-square analysis was conducted. Use the chi-square distribution to determine rejection region when testing at α=0.025\alpha = 0.025 .


A) Reject H0\mathrm { H } _ { 0 } if χ2>12.8325\chi ^ { 2 } > 12.8325
B) Reject H0\mathrm { H } _ { 0 } if χ2>14.4494\chi ^ { 2 } > 14.4494
C) Reject H0\mathrm { H } _ { 0 } if χ2>11.1433\chi ^ { 2 } > 11.1433
D) Reject H0\mathrm { H } _ { 0 } if χ2>9.48773\chi ^ { 2 } > 9.48773

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