The reaction of what nucleophile and substrate is represented by the following transition state?

Question

Quizplus · Accepted Answer

The reaction involves the substitution of a bromine atom in a substrate by a nucleophile. The presence of a transition state indicates that the reaction proceeds through an intermediate state where the bond between the substrate and the leaving group begins to break, while simultaneously forming a bond between the substrate and the incoming nucleophile. In this case, the transition state is characterized by the presence of a methoxide anion approaching the substrate (2-bromopropane), suggesting that the reaction involves a nucleophilic substitution by methoxide. Therefore, the correct answer is B, which corresponds to the reaction of methoxide with 2-bromopropane.

The Reaction of What Nucleophile and Substrate Is Represented by the Following