Rank the following groups in order of decreasing priority according to the Cahn-Ingold-Prelog system.

Question

Quizplus · Accepted Answer

According to the Cahn-Ingold-Prelog system, priority is determined by looking at the atomic number of the atoms directly attached to the stereocenter. In this case, group IV has two carbon atoms directly attached to the stereocenter, both of which are higher priority than the single carbon attached to groups I, II, and III. Therefore, group IV has the highest priority. Group III has a nitrogen directly attached to the stereocenter, which has a higher atomic number than carbon, giving it the second highest priority. Group I has a single carbon directly attached to the stereocenter, giving it the third highest priority, and group II has a hydrogen directly attached, giving it the lowest priority. Therefore, the correct ranking is IV > III > I > II, or choice C.

Rank the Following Groups in Order of Decreasing Priority According