If a Claisen condensation reaction is run using methyl propanoate as the reactant, NaOCH 3 is the ideal base.Why is it important to use NaOCH 3 and not NaOCH 2 CH 3 ?

NaOCH 2 CH 3 can lead to transesterification, which would result in a mixture of products. Using NaOCH 3 helps to prevent this from happening. The other options given are incorrect.

If a Claisen condensation reaction is run using methyl propanoate as the reactant, NaOCH 3 is the ideal base.Why is it important to use NaOCH 3 and not NaOCH 2 CH 3 ?

NaOCH 2 CH 3 can lead to transesterification, which would result in a mixture of products. Using NaOCH 3 helps to prevent this from happening. The other options given are incorrect.

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If a Claisen Condensation Reaction Is Run Using Methyl

Question 44

Multiple Choice

If a Claisen condensation reaction is run using methyl propanoate as the reactant, NaOCH₃ is the ideal base.Why is it important to use NaOCH₃ and not NaOCH₂CH₃?

A) NaOCH₃ is a stronger base than NaOCH₂CH₃, and this reaction requires a stronger base.
B) NaOCH₃ is a weaker base than NaOCH₂CH₃, and this reaction requires a weaker base.
C) Transesterfication can occur when esters react, and this transesterfication would result in a mixture of products.
D) NaOCH₃ is more soluble than NaOCH₂CH₃ in organic solvents, and this reaction requires a full equivalent of base to proceed.A full equivalent of NaOCH₂CH₃ would not dissolve, so the reaction would not proceed.