T-Cell and B-Cell Lymphocytes Are the Primary Participants in the Immune

T-cell and B-cell lymphocytes are the primary participants in the immune response. What do they do?

A) T-cell and B-cell lymphocytes distinguish harmful substances and ignore those natural and unique to a person.
B) T-cell and B-cell lymphocytes respond to the body's invasion by macrophages.
C) T-cell and B-cell lymphocytes react to the body's lack of B .12
D) T-cell and B-cell lymphocytes distinguish harmful treatments from curative treatments.