The major category(ies) of hypersensitivity(ies) that typically involve(s) a B-cell immunoglobulin response include(s) _______.

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Type I, type II, and type III hypersensitivities involve B-cell immunoglobulin responses. Type I involves IgE-mediated reactions, type II involves IgG or IgM antibodies directed against cell surface or extracellular matrix antigens, and type III involves immune complex-mediated reactions. Type IV hypersensitivity is cell-mediated and does not involve B-cell immunoglobulin responses.

The Major Category(ies) of Hypersensitivity(ies) That Typically Involve(s) a B-Cell