Noncompetitive inhibition is best described as _______.

Question

Quizplus · Accepted Answer

Noncompetitive inhibition occurs when an inhibitor binds to an enzyme at a site other than the active site, which is often referred to as an allosteric site. This binding changes the shape of the enzyme in such a way that even if the substrate can still bind to the active site, the enzyme is no longer in a proper configuration to catalyze the reaction efficiently. This is different from competitive inhibition, where the inhibitor competes directly with the substrate for the active site. Option D accurately describes this process, with the "end product" acting as the inhibitor that binds to a noncompetitive site on the enzyme, altering its activity without directly competing with the substrate for the active site.

Noncompetitive Inhibition Is Best Described as _______