Below is a metabolic pathway having 3 chemical reactions and 3 enzymes. Enzyme 1 has 2 binding sites--1 for the substrate A and another for the end product D. As the pathway proceeds, the end product in higher quantities will react with enzyme 1, blocking the enzyme's binding to the substrate.
Which statement is true about this pathway?

$\quad $$\quad $$\quad $enz1 $\quad $enz2 $\quad $enz3
Substrate A -- B -- C -- D end product

Question

Below is a metabolic pathway having 3 chemical reactions and 3 enzymes. Enzyme 1 has 2 binding sites--1 for the substrate A and another for the end product D. As the pathway proceeds, the end product in higher quantities will react with enzyme 1, blocking the enzyme's binding to the substrate.
Which statement is true about this pathway?

$\quad $$\quad $$\quad $enz1 $\quad $enz2 $\quad $enz3
Substrate A --> B --> C --> D end product

Quizplus · Accepted Answer

The description matches noncompetitive inhibition because the end product D binds to a site other than the active site on enzyme 1, which is characteristic of noncompetitive inhibition. This binding will decrease the overall conversion of substrate A to the end product D, indicating that the pathway is regulated through feedback inhibition. Enzyme 1 having two binding sites—one for the substrate and another for the end product—indicates it has an active site and a regulatory site. Therefore, all provided statements are correct.

Below Is a Metabolic Pathway Having 3 Chemical Reactions and 3