A 4-Year-Old Child Has Clusters of Small, Clear, Tense Vesicles

A 4-year-old child has clusters of small, clear, tense vesicles with an erythematous base on one side of the mouth along the vermillion border, which are causing discomfort and difficulty eating. What will the primary care pediatric nurse practitioner recommend as treatment?

A) Mupirocin ointment applied to lesions 3 times daily
B) Oral acyclovir 20 to 40 mg/kg/dose for 7 to 10 days
C) Topical acyclovir applied to lesions 4 times daily
D) Topical diphenhydramine and magnesium hydroxide