How does lipid phosphatase PTEN affect the balance between proapoptotic and antiapoptotic signals?
A) PTEN removes the phosphate group from the 3-position of PIP3 converting it to PI(4,5) P2, which cannot activate PKB (AKT) and thus throws the balance in an antiapoptotic direction.
B) PTEN removes the phosphate group from the 3-position of PIP3 converting it to PI(4,5) P2, which cannot activate PKB (AKT) and thus throws the balance in a proapoptotic direction.
C) PTEN cuts a phosphate group off of PKB, which throws the balance in a proapoptotic direction.
D) PTEN cuts a phosphate group off of PKB, which throws the balance in an antiapoptotic direction.
E) PTEN adds a phosphate group to PKB, which throws the balance in a proapoptotic direction.
Correct Answer:
Verified
Q38: Which of the following is true of
Q39: Scientists in the late 1960's were studying
Q40: _ is an inherited disease in which
Q41: Because they act to _ tumorigenesis, the
Q42: The avian erythroblastosis virus contains an oncogene
Q44: A well-known cell-survival pathway involves a kinase
Q45: What commonly happens to the number of
Q46: Which of the following enzymes is known
Q47: How are drug companies trying to combat
Q48: What virus seems to be related to
Unlock this Answer For Free Now!
View this answer and more for free by performing one of the following actions
Scan the QR code to install the App and get 2 free unlocks
Unlock quizzes for free by uploading documents