In order to begin desensitization, the ________ domain of the activated G protein-coupled receptor is phosphorylated by a specific enzyme called a ________.
A)extracellular, G protein-coupled receptor kinase
B)extracellular, G protein-coupled receptor phosphatase
C)cytoplasmic, G protein-coupled receptor kinase
D)cytoplasmic, G protein-coupled receptor phosphatase
E)extracellular, GRK

Question

Quizplus · Accepted Answer

In order to begin desensitization, the cytoplasmic domain of the activated G protein-coupled receptor is phosphorylated by a specific enzyme called a G protein-coupled receptor kinase (GRK). Therefore, the best choice is C, which correctly identifies the domain and enzyme involved in receptor phosphorylation during desensitization.

In Order to Begin Desensitization, the ________ Domain of the Activated