Epithelial cell division and turnover is thought to be regulated through the activity of:
A)voltage-gated channels
B)ligand-gated channels
C)mechano-gated channels
D)all are correct choices

Question

Quizplus · Accepted Answer

Mechano-gated channels are activated or regulated by mechanical stimuli, such as changes in pressure, tension, or stretch. Epithelial cells are subjected to physical forces and stresses due to mechanical deformation caused by movement, expansion, or contraction of tissues, as well as external factors such as fluid flow or shearing forces from air or fluid turbulence. These mechanical cues can trigger changes in ion channels or intracellular signaling pathways, leading to alterations in cell shape, migration, adhesion, or proliferation, which are important for maintaining tissue homeostasis and repair. Therefore, mechano-gated channels are likely to play a key role in epithelial cell division and turnover, although other channels or receptors may also be involved. Voltage-gated or ligand-gated channels are less likely to be directly linked to mechanical signaling in this context.

Epithelial Cell Division and Turnover Is Thought to Be Regulated