Cultured mammalian cells grown in thymidine for many generations were allowed to undergo replication in the presence of bromodeoxyuridine (BrdU), which replaces thymidine in DNA. After one round of replication, what would the DNA look like if replication were dispersive?

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If replication were dispersive, both strands of each chromatid would contain a mixture of BrdU and thymidine. During dispersive replication, the parental DNA strands are broken apart into smaller pieces, which are then used as templates for the synthesis of new strands. As a result, each of the new double helices formed will contain a mixture of DNA from the parental strands and the newly synthesized strands. Therefore, after one round of replication in the presence of BrdU, both strands of each chromatid would contain a mixture of BrdU and thymidine if replication were dispersive.

Cultured Mammalian Cells Grown in Thymidine for Many Generations Were