What happens simultaneously with the removal of RNA primer by the 5'-3' exonuclease activity of DNA polymerase I?
A)The DNA double helix is unwound.
B)The gap left by the removal of the RNA primer is filled in with deoxyribonucleotides.
C)The gap left by the removal of the RNA primer is filled in with ribonucleotides.
D)DNA is supercoiled extensively.

Question

What happens simultaneously with the removal of RNA primer by the 5'->3' exonuclease activity of DNA polymerase I?
A)The DNA double helix is unwound.
B)The gap left by the removal of the RNA primer is filled in with deoxyribonucleotides.
C)The gap left by the removal of the RNA primer is filled in with ribonucleotides.
D)DNA is supercoiled extensively.

Quizplus · Accepted Answer

The removal of the RNA primer by the 5'->3' exonuclease activity of DNA polymerase I creates a gap in the newly synthesized DNA strand. This gap is then filled in with deoxyribonucleotides by DNA polymerase I, which also has 5'->3' polymerase activity. Therefore, choice B is correct. The other choices are not related to this specific process.

What Happens Simultaneously with the Removal of RNA Primer by the 5'->3