The DNA Polymerases Is a Relatively Large Family of Polymerases

The DNA polymerases is a relatively large family of polymerases in which each member is specialized for incorporating nucleotides opposite particular types of DNA lesions in the template strand engage in a type of DNA synthesis called __________. They have an unusually spacious active site that ____________.

A) translesion synthesis; unwinds DNA double helices
B) translesion synthesis; is able to physically accommodate altered nucleotides that would not fit in the active site of a replicative polymerase
C) transdimensional synthesis; incorporates the nucleotide that would have paired with the undamaged version of the template base
D) transdimensional synthesis; unwinds DNA synthesis
E) transliteral synthesis; is able to physically accommodate altered nucleotides that would not fit in the active site of a replicative polymerase