How is the RISC directed to the target mRNA that it is destined to destroy?
A)The ribonuclease slicer directs the RISC to the cleavage site.
B)The single-stranded siRNA is complementary to the target mRNA and directs the RISC to it.
C)The passenger strand acts like a guide to direct the RISC to the target.
D)The siRNA is complementary to the slicer ribonuclease.
E)The siRNA is magnetically attracted to the target mRNA.

Question

Quizplus · Accepted Answer

The single-stranded siRNA is complementary to the target mRNA and directs the RISC to it through base pairing. This allows for specific targeting and degradation of the target mRNA. The other options are either not involved in directing the RISC to the target mRNA or are incorrect in their mechanisms.

How Is the RISC Directed to the Target MRNA That