Based on the interchangeability of the nucleotide at the third position, Francis Crick proposed that the same tRNA may be able to recognize more than one codon. What was his proposal called?
A)the tRNA theory
B)the wobble hypothesis
C)the steric hindrance hypothesis
D)the chemiosmotic hypothesis
E)the endosymbiotic hypothesis

Question

Quizplus · Accepted Answer

Crick's proposal was called the wobble hypothesis, which states that the third nucleotide in a codon and the first nucleotide in the anticodon of tRNA can exhibit non-Watson-Crick base pairing, allowing for some flexibility in codon-anticodon interactions. This allows one tRNA molecule to recognize multiple codons.

Based on the Interchangeability of the Nucleotide at the Third