Given that axons growing out of a neuron require the outward growth of microtubules to support the lengtheningaxon, what would be likely to happen to axons growing out from a neuron when they are exposed to colchicine or nocodazole?
A)Axons would grow more rapidly.
B)Axonal outgrowth would cease.
C)Axons would branch more often.
D)Axonal outgrowth would change direction more frequently.
E)There would be no change in axonal outgrowth.

Question

Quizplus · Accepted Answer

Colchicine and nocodazole both destabilize microtubules by binding to tubulin and preventing their polymerization. Since microtubules are necessary for the outward growth of axons, exposing axons to these drugs would cause axonal outgrowth to cease.

Given That Axons Growing Out of a Neuron Require the Outward